The reasons on advise to apply AI Denoise early in the workflow are as follow:
AI-driven, image-based features such as Content-Aware Remove and Select Subject can be affected by noise, so itโs best to use those features on a clean starting point. If you do run Denoise on an image that already has Content-Aware Remove settings or AI masks, Denoise will automatically update those spots and masks. It is handy but we have to keep an eye on them. Also Denoise sometimes subtly change the overall tonality of the photo, especially by cleaning up the shadows. If your source photo already had major tonal adjustments, such as with Shadows, Clarity, or Dehaze, you may need to revisit those settings after applying Denoise.
This from Adobe website.