Hey knickerhawk! Didn't know you posted here! In the quote from your link, I do take issue with the latter portion:
Given that light is being collected from a smaller area of the slide at higher magnifications, the larger pixels will also contribute towards increased sensitivity of the camera. This lends itself well to other applications where low light is an issue and high sensitivity is required.
This will be true if the aggregate electronic noise from the smaller pixels covering the same area as the larger pixels is greater than the electronic noise from the larger pixels covering the same area. If the electronic noise for a 1x1 pixel is half the electronic noise as a 2x2 pixel, then the electronic noise will be the same. I don't know how this pans out in practice, however. Regardless, this would only be an issue in very low light, and my understanding is that most microscopy is performed with copious amounts of light (either via longer total exposure time or large amounts of external light added) so that it is a non-issue.
Typically, with "normal" photography, even if the smaller pixels are intrinsically more noisy for a given area, noise filtering will work better on the more detailed photo resulting in an overall benefit for more smaller pixels, even when more intrinsically noisy. However, this presumes there is "enough" detail to gain the benefits of the noise filtering. For a photo that is deep in the realm of diffraction softening, there may not be enough detail for this benefit to be manifest beyond a certain pixel count.