There were rumours the X-E line might be continued when all that followed the X-E2 was the minor refresh in the X-E2s.
Still, soon after the X-E3 was announced.
From what I've gathered online, it feels like there was more enthusiasm for the X-E4 than there was the X-E3.
Sure, the enthusiast crowd and passionate X-E owners (myself included) were sceptical/critical of the new trajectory of the product line. But I feel like there was a larger buzz and demand for the X-E4.
Of course this is just reading tea leaves, but I'd be surprised and disappointed if this was the end of the line.
Maybe it's just wishful thinking, but I rather expect Fuji to have run out of supply (like they have with other models in the past) before being ready to announce the successor.
And as much as I'd personally appreciate an X-E "Pro", i.e. an X-Pro with just an EVF, I don't see Fuji adding such a model, nor transforming the X-Pro into such a body. There are plenty of EVF-only bodies (albeit not rangefinder styled) in the mid and top range to choose from, while the hybrid viewfinder is a USP.